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We are able to offer a variety of cruises through the Panama Canal. The Panama Canal is the perfect setting for your unforgettable cruise adventure.
Cutting along the "Crossroads of the Americas”, the Panama Canal is one of the most important shipping routes in the world. This mesmerising feat of engineering is steeped in history, surrounded at every turn by breathtaking natural beauty, cosmopolitan allure and crumbling, colonial towns.
Stretching across the continent, Panama’s coastlines dip into the warm waters of the Caribbean on one side and the wild, Pacific surf on the other. Along the interior, the Canal passes through a belt of coffee-growing plantations and lush, emerald rainforest, humid and humming with tropical wildlife.
The sleek skyline of the capital, Panama City, soars above the turquoise Pacific, a tropical hub of trendy cafés and stylish wine bars. A pastel-coloured old quarter unwinds into a maze of peeling colonial buildings, whitewashed cathedrals and treasure-laden museums. Nearby, the crumbling ruins of Panamá Viejo, the original city sacked by pirates take you back to a forgotten time. Tucked against the Caribbean Sea, the intriguing city of Colón is backed by lush rainforest canopies filled with scrambling monkeys, sublime cloud forests and indigenous territories.
Give us a call today on 01903 694322 to book your Panama Canal cruise.
23rd September 2025 for 23 nights | |
Caribbean Princess | |
Vancouver, British Columbia ~ San Francisco, California ~ Santa Catalina Island, California ~ San Diego, California ~ Los Angeles, California ~ Puerto Vallarta ~ Huatulco (Santa María Huatulco) ~ Puerto Chiapas ~ Puntarenas ~ Fuerte Amador ~ ~ Aruba ~ Fort Lauderdale, Florida | |
Cruise Only from Interior Call Oceanview £1,098pp Balcony Call Suite Call Please Call for Flights |
25th September 2025 for 33 nights | |
Queen Elizabeth | |
Seattle, Washington ~ San Francisco, California ~ Los Angeles, California ~ Cabo San Lucas ~ Puntarenas ~ ~ Curaçao ~ Aruba ~ Miami, Florida ~ San Juan (Puerto Rico) ~ Saint John's ~ Castries ~ Bridgetown ~ Sint Maarten ~ Tortola ~ Miami, Florida | |
Please call for availability |
25th September 2025 for 21 nights | |
Queen Elizabeth | |
Seattle, Washington ~ San Francisco, California ~ Los Angeles, California ~ Cabo San Lucas ~ Puntarenas ~ ~ Curaçao ~ Aruba ~ Miami, Florida | |
Cruise Only from Interior £1,499pp Oceanview £1,699pp Balcony Call Suite Call Fly/Cruise | |
Fly/Cruise from Interior £2,909pp Oceanview £3,109pp Balcony Call Suite Call Fly/Cruise |
28th September 2025 for 18 nights | |
Queen Elizabeth | |
San Francisco, California ~ Los Angeles, California ~ Cabo San Lucas ~ Puntarenas ~ ~ Curaçao ~ Aruba ~ Miami, Florida | |
Please call for availability |
28th September 2025 for 30 nights | |
Queen Elizabeth | |
San Francisco, California ~ Los Angeles, California ~ Cabo San Lucas ~ Puntarenas ~ ~ Curaçao ~ Aruba ~ Miami, Florida ~ San Juan (Puerto Rico) ~ Saint John's ~ Castries ~ Bridgetown ~ Sint Maarten ~ Tortola ~ Miami, Florida | |
Please call for availability |
30th September 2025 for 16 nights | |
Caribbean Princess | |
Los Angeles, California ~ Puerto Vallarta ~ Huatulco (Santa María Huatulco) ~ Puerto Chiapas ~ Puntarenas ~ Fuerte Amador ~ ~ Aruba ~ Fort Lauderdale, Florida | |
Cruise Only from Interior £757pp Oceanview £780pp Balcony Call Suite Call Please Call for Flights |
4th October 2025 for 22 nights | |
Eurodam | |
Seattle, Washington ~ Vancouver, British Columbia ~ Santa Barbara, California ~ San Diego, California ~ Puerto Vallarta ~ Huatulco (Santa María Huatulco) ~ Puerto Chiapas ~ Puerto Quetzal ~ Acajutla ~ Puntarenas ~ Aruba ~ Fort Lauderdale, Florida | |
Please call for availability |
4th October 2025 for 16 nights | |
Radiance of the Seas | |
San Diego, California ~ Cabo San Lucas ~ Mazatlán ~ Puerto Quetzal ~ Puntarenas ~ ~ Colón ~ Cartagena ~ Georgetown, Grand Cayman ~ Fort Lauderdale, Florida | |
Cruise Only from Interior £1,848pp Oceanview Call Balcony Call Suite Call Please Call for Flights |
5th October 2025 for 21 nights | |
Eurodam | |
Vancouver, British Columbia ~ Santa Barbara, California ~ San Diego, California ~ Puerto Vallarta ~ Huatulco (Santa María Huatulco) ~ Puerto Chiapas ~ Puerto Quetzal ~ Acajutla ~ Puntarenas ~ Aruba ~ Fort Lauderdale, Florida | |
Please call for availability |
6th October 2025 for 16 nights | |
Carnival Legend | |
San Francisco, California ~ Cabo San Lucas ~ Puntarenas ~ ~ Cartagena ~ Grand Cayman ~ Galveston, Texas | |
Please call for availability |
9th October 2025 for 17 nights | |
Eurodam | |
San Diego, California ~ Puerto Vallarta ~ Huatulco (Santa María Huatulco) ~ Puerto Chiapas ~ Puerto Quetzal ~ Acajutla ~ Puntarenas ~ Aruba ~ Fort Lauderdale, Florida | |
Cruise Only from Interior £2,729pp Oceanview £2,789pp Balcony Call Suite £7,019pp Please Call for Flights |
11th October 2025 for 16 nights | |
Carnival Spirit | |
Seattle, Washington ~ Cabo San Lucas ~ Puntarenas ~ ~ Cartagena ~ New Orleans, Louisiana | |
Please call for availability |
16th October 2025 for 12 nights | |
Caribbean Princess | |
Fort Lauderdale, Florida ~ Aruba ~ Curaçao ~ Cartagena ~ ~ Colón ~ Puerto Limón ~ Grand Cayman ~ Fort Lauderdale, Florida | |
Cruise Only from Interior £778pp Oceanview Call Balcony Call Suite Call Please Call for Flights |
Interior | Oceanview | Balcony | Suite | |
(All prices are £GBP per person) | ||||
Tue 23rd Dec 202523 Dec 25 | Call | 1,444 | 2,287 | 2,998 |
Sun 4th Jan 202604 Jan 26 | 919 | 1,515 | Call | Call |
21st October 2025 for 23 nights | |
Coral Princess | |
Vancouver, British Columbia ~ San Francisco, California ~ San Diego, California ~ Santa Barbara, California ~ Los Angeles, California ~ Puerto Vallarta ~ Huatulco (Santa María Huatulco) ~ Puerto Chiapas ~ Puntarenas ~ Fuerte Amador ~ ~ Aruba ~ Fort Lauderdale, Florida | |
Cruise Only from Interior £1,407pp Oceanview £1,489pp Balcony Call Suite £2,023pp Please Call for Flights |
22nd October 2025 for 16 nights | |
Island Princess | |
Los Angeles, California ~ Puerto Vallarta ~ Huatulco (Santa María Huatulco) ~ Puerto Chiapas ~ Puntarenas ~ Fuerte Amador ~ ~ Curaçao ~ Fort Lauderdale, Florida | |
Cruise Only from Interior £782pp Oceanview £756pp Balcony £919pp Suite £1,035pp Please Call for Flights |
26th October 2025 for 12 nights | |
Rotterdam | |
Fort Lauderdale, Florida ~ Half Moon Cay ~ Curaçao ~ Cartagena ~ Gatun Lake ~ ~ Gatun Lake ~ Colón ~ Puerto Limón ~ Grand Cayman ~ Fort Lauderdale, Florida | |
Cruise Only from Interior £2,269pp Oceanview £2,669pp Balcony £2,869pp Suite Call Please Call for Flights |
Interior | Oceanview | Balcony | Suite | |
(All prices are £GBP per person) | ||||
Sun 7th Dec 202507 Dec 25 | 2,219 | 2,629 | 2,789 | 3,589 |
Sun 8th Feb 202608 Feb 26 | 2,629 | 3,349 | 3,589 | Call |
Sun 1st Mar 202601 Mar 26 | 2,629 | 3,349 | 3,589 | 4,429 |
28th October 2025 for 16 nights | |
Coral Princess | |
Los Angeles, California ~ Puerto Vallarta ~ Huatulco (Santa María Huatulco) ~ Puerto Chiapas ~ Puntarenas ~ Fuerte Amador ~ ~ Aruba ~ Fort Lauderdale, Florida | |
Cruise Only from Interior £965pp Oceanview £921pp Balcony £1,149pp Suite £1,199pp Please Call for Flights |
Interior | Oceanview | Balcony | Suite | |
(All prices are £GBP per person) | ||||
Tue 29th Sep 202629 Sep 26 | 1,299 | 1,432 | 2,219 | 2,452 |
1st November 2025 for 14 nights | |
Royal Clipper | |
Bridgetown ~ Soufrière ~ Tobago Cays ~ Saint George's ~ Kralendijk ~ Willemstad ~ Oranjestad ~ Santa Marta ~ Cartagena ~ San Blas Islands ~ Balboa (Panama City) | |
Please call for availability |
Sat 31st Oct 202631 Oct 26 | Please call for availability |
1st November 2025 for 17 nights | |
Koningsdam | |
San Diego, California ~ Puerto Vallarta ~ Huatulco (Santa María Huatulco) ~ Puerto Chiapas ~ Puerto Quetzal ~ Puntarenas ~ Aruba ~ Half Moon Cay ~ Fort Lauderdale, Florida | |
Cruise Only from Interior £2,559pp Oceanview £2,959pp Balcony £2,959pp Suite £4,509pp Please Call for Flights |
2nd November 2025 for 16 nights | |
Emerald Princess | |
Fort Lauderdale, Florida ~ Aruba ~ ~ Fuerte Amador ~ Puntarenas ~ Puerto Chiapas ~ Huatulco (Santa María Huatulco) ~ Puerto Vallarta ~ Los Angeles, California | |
Cruise Only from Interior £762pp Oceanview £690pp Balcony £1,285pp Suite £1,449pp Please Call for Flights |
15th November 2025 for 14 nights | |
Royal Clipper | |
Balboa (Panama City) ~ San Blas Islands ~ Cartagena ~ Santa Marta ~ Oranjestad ~ Willemstad ~ Kralendijk ~ Saint George's ~ Soufrière ~ Deshaies ~ Saint John's | |
Please call for availability |
17th November 2025 for 12 nights | |
Caribbean Princess | |
Fort Lauderdale, Florida ~ Aruba ~ Curaçao ~ Cartagena ~ ~ Colón ~ Puerto Limón ~ Ocho Rios ~ Fort Lauderdale, Florida | |
Cruise Only from Interior £644pp Oceanview £671pp Balcony £949pp Suite £1,399pp Please Call for Flights |
17th November 2025 for 17 nights | |
Oosterdam | |
Fort Lauderdale, Florida ~ Grand Cayman ~ Fuerte Amador ~ Manta ~ Salaverry ~ Callao ~ General San Martin ~ Coquimbo ~ San Antonio | |
Cruise Only from Interior £2,519pp Oceanview £2,599pp Balcony £2,919pp Suite £3,789pp Please Call for Flights |
21st November 2025 for 16 nights | |
Island Princess | |
Fort Lauderdale, Florida ~ Cartagena ~ ~ Fuerte Amador ~ Puntarenas ~ Puerto Quetzal ~ Manzanillo, Mexico ~ San Francisco, California | |
Cruise Only from Interior £891pp Oceanview £873pp Balcony £1,270pp Suite £1,565pp Please Call for Flights |
21st November 2025 for 10 nights | |
Norwegian Jewel | |
Miami, Florida ~ Cartagena ~ Gatun Lake ~ Colón ~ Puerto Limón ~ Harvest Caye ~ Cozumel ~ Miami, Florida | |
Cruise Only from Interior £747pp Oceanview £858pp Balcony £1,774pp Suite £2,106pp Please Call for Flights |
Fusion Cruises when selling travel arrangements is a trading name of The Midcounties Co-operative Ltd. Fusion Cruises is an Accredited Body Member of Midcounties Co-operative Travel Consortium. (ABTA:P6652, ATOL:6053).
Book with Confidence. We are a Member of ABTA which means you have the benefit of ABTA’s assistance and Code of Conduct.
Some of the flights and flight-inclusive holidays on this website are financially protected by the ATOL scheme but ATOL protection does not apply to all holiday and travel services offered on this website. This website will provide you with information on the protection that applies in the case of each holiday and travel service offered before you make your booking. If you do not receive an ATOL Certificate then the booking will not be ATOL protected. If you do receive an ATOL Certificate but all parts of your trip are not listed on it, those parts will not be ATOL protected. Please see our booking conditions for information, or for more information about financial protection and the ATOL Certificate go to: www.caa.co.uk