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We are able to offer a variety of cruises through the Panama Canal. The Panama Canal is the perfect setting for your unforgettable cruise adventure.
Cutting along the "Crossroads of the Americas”, the Panama Canal is one of the most important shipping routes in the world. This mesmerising feat of engineering is steeped in history, surrounded at every turn by breathtaking natural beauty, cosmopolitan allure and crumbling, colonial towns.
Stretching across the continent, Panama’s coastlines dip into the warm waters of the Caribbean on one side and the wild, Pacific surf on the other. Along the interior, the Canal passes through a belt of coffee-growing plantations and lush, emerald rainforest, humid and humming with tropical wildlife.
The sleek skyline of the capital, Panama City, soars above the turquoise Pacific, a tropical hub of trendy cafés and stylish wine bars. A pastel-coloured old quarter unwinds into a maze of peeling colonial buildings, whitewashed cathedrals and treasure-laden museums. Nearby, the crumbling ruins of Panamá Viejo, the original city sacked by pirates take you back to a forgotten time. Tucked against the Caribbean Sea, the intriguing city of Colón is backed by lush rainforest canopies filled with scrambling monkeys, sublime cloud forests and indigenous territories.
Give us a call today on 01903 694322 to book your Panama Canal cruise.
2nd April 2025 for 10 nights | |
Sirena | |
Panama City ~ ~ Cartagena ~ Santa Marta ~ Oranjestad ~ Willemstad ~ Kralendijk ~ ~ Port Antonio ~ ~ Miami, Florida | |
Cruise Only from Interior Call Oceanview Call Balcony £4,489pp Suite Call Fly/Cruise | |
Fly/Cruise from Interior Call Oceanview Call Balcony £6,219pp Suite Call Fly/Cruise |
2nd April 2025 for 10 nights | |
Zaandam | |
San Diego, California ~ Cabo San Lucas ~ La Paz ~ Loreto ~ Puerto Vallarta ~ Mazatlán ~ San Diego, California | |
Cruise Only from Interior Call Oceanview £1,749pp Suite £3,559pp Please Call for Flights |
7th April 2025 for 11 nights | |
Celebrity Beyond | |
Fort Lauderdale, Florida ~ Cartagena ~ ~ Colón ~ Oranjestad ~ Willemstad ~ Kralendijk ~ Fort Lauderdale, Florida | |
Cruise Only from Interior Call Oceanview £1,678pp Balcony £2,241pp Suite Call Fly/Cruise | |
Fly/Cruise from Interior Call Oceanview £3,303pp Balcony £3,866pp Suite Call Fly/Cruise |
9th April 2025 for 19 nights | |
Seabourn Encore | |
Long Beach, California ~ Puerto Vallarta ~ Huatulco (Santa María Huatulco) ~ Puerto Chiapas ~ Puerto Quetzal ~ Puntarenas ~ Cartagena ~ Miami, Florida | |
Cruise Only from Balcony £6,599pp Suite Call Please Call for Flights |
10th April 2025 for 23 nights | |
Coral Princess | |
Fort Lauderdale, Florida ~ Aruba ~ ~ Fuerte Amador ~ Puntarenas ~ Puerto Chiapas ~ Huatulco (Santa María Huatulco) ~ Puerto Vallarta ~ Los Angeles, California ~ San Diego, California ~ San Francisco, California ~ Astoria, Oregon ~ Victoria, British Columbia ~ Vancouver, British Columbia | |
Cruise Only from Interior £1,619pp Oceanview £1,719pp Balcony Call Suite Call Please Call for Flights |
10th April 2025 for 16 nights | |
Coral Princess | |
Fort Lauderdale, Florida ~ Aruba ~ ~ Fuerte Amador ~ Puntarenas ~ Puerto Chiapas ~ Huatulco (Santa María Huatulco) ~ Puerto Vallarta ~ Los Angeles, California | |
Cruise Only from Interior Call Oceanview £1,259pp Balcony £1,299pp Suite £2,099pp Please Call for Flights |
12th April 2025 for 14 nights | |
Eurodam | |
Fort Lauderdale, Florida ~ Cartagena ~ Puntarenas ~ Puerto Quetzal ~ Huatulco (Santa María Huatulco) ~ Puerto Vallarta ~ San Diego, California | |
Please call for availability |
Interior | Oceanview | Balcony | Suite | |
(All prices are £GBP per person) | ||||
Sat 3rd Apr 202703 Apr 27 | 2,989 | 3,339 | 4,239 | 5,989 |
12th April 2025 for 21 nights | |
Eurodam | |
Fort Lauderdale, Florida ~ Cartagena ~ Puntarenas ~ Puerto Quetzal ~ Huatulco (Santa María Huatulco) ~ Puerto Vallarta ~ San Diego, California ~ San Francisco, California ~ Victoria, British Columbia ~ Vancouver, British Columbia ~ Seattle, Washington | |
Please call for availability |
12th April 2025 for 20 nights | |
Eurodam | |
Fort Lauderdale, Florida ~ Cartagena ~ Puntarenas ~ Puerto Quetzal ~ Huatulco (Santa María Huatulco) ~ Puerto Vallarta ~ San Diego, California ~ San Francisco, California ~ Victoria, British Columbia ~ Vancouver, British Columbia | |
Please call for availability |
13th April 2025 for 16 nights | |
Serenade of the Seas | |
Fort Lauderdale, Florida ~ Georgetown, Grand Cayman ~ Cartagena ~ Colón ~ ~ Puerto Quetzal ~ Puerto Vallarta ~ Cabo San Lucas ~ Los Angeles, California | |
Cruise Only from Interior £2,333pp Oceanview Call Balcony Call Suite Call Please Call for Flights |
13th April 2025 for 17 nights | |
Nieuw Amsterdam | |
Fort Lauderdale, Florida ~ Grand Turk Island ~ Aruba ~ Cartagena ~ Puntarenas ~ Acajutla ~ Puerto Vallarta ~ Cabo San Lucas ~ San Diego, California | |
Please call for availability |
13th April 2025 for 21 nights | |
Nieuw Amsterdam | |
Fort Lauderdale, Florida ~ Grand Turk Island ~ Aruba ~ Cartagena ~ Puntarenas ~ Acajutla ~ Puerto Vallarta ~ Cabo San Lucas ~ San Diego, California ~ Victoria, British Columbia ~ Vancouver, British Columbia | |
Please call for availability |
14th April 2025 for 16 nights | |
Caribbean Princess | |
Port Canaveral, Florida ~ Nassau ~ Cartagena ~ ~ Fuerte Amador ~ Puntarenas ~ Huatulco (Santa María Huatulco) ~ Puerto Vallarta ~ Los Angeles, California | |
Please call for availability |
14th April 2025 for 21 nights | |
Caribbean Princess | |
Port Canaveral, Florida ~ Nassau ~ Cartagena ~ ~ Fuerte Amador ~ Puntarenas ~ Huatulco (Santa María Huatulco) ~ Puerto Vallarta ~ Los Angeles, California ~ San Francisco, California ~ Victoria, British Columbia ~ Vancouver, British Columbia | |
Please call for availability |
17th April 2025 for 16 nights | |
Celebrity Summit | |
Fort Lauderdale, Florida ~ Georgetown, Grand Cayman ~ Cartagena ~ Colón ~ ~ Puntarenas ~ Puerto Quetzal ~ Mazatlán ~ Los Angeles, California | |
Please call for availability |
19th April 2025 for 11 nights | |
Greg Mortimer | |
San José ~ Curú Wildlife Refuge ~ Manuel Antonio National Park ~ Punta Rio Claro National Wildlife Refuge ~ Golfo Dulce ~ Coiba Island ~ Pearl Islands ~ Panama City ~ ~ Panama City | |
Please call for availability |
19th April 2025 for 15 nights | |
Radiance of the Seas | |
Tampa, Florida ~ Georgetown, Grand Cayman ~ Cartagena ~ Colón ~ ~ Puerto Quetzal ~ Puerto Vallarta ~ Los Angeles, California | |
Please call for availability |
24th April 2025 for 14 nights | |
Carnival Legend | |
Tampa, Florida ~ Cartagena ~ ~ Puntarenas ~ Cabo San Lucas ~ San Francisco, California | |
Please call for availability |
17th May 2025 for 18 nights | |
Island Princess | |
Los Angeles, California ~ Puerto Vallarta ~ Huatulco (Santa María Huatulco) ~ Puerto Chiapas ~ Puntarenas ~ Fuerte Amador ~ ~ Aruba ~ New York, New York | |
Cruise Only from Interior Call Oceanview £1,359pp Balcony Call Suite Call Please Call for Flights |
6th June 2025 for 18 nights | |
Seven Seas Mariner | |
San Francisco, California ~ ~ Los Angeles, California ~ Ensenada ~ ~ Cabo San Lucas ~ ~ Acapulco ~ ~ Puerto Quetzal ~ Corinto ~ Puntarenas ~ ~ Cartagena ~ ~ Georgetown, Grand Cayman ~ ~ Miami, Florida | |
Please call for availability |
3rd July 2025 for 20 nights | |
Insignia | |
San Diego, California ~ ~ Cabo San Lucas ~ ~ Zihuatanejo ~ ~ Puerto Quetzal ~ Corinto ~ Puntarenas ~ ~ Cartagena ~ ~ Georgetown, Grand Cayman ~ ~ Miami, Florida ~ Port Canaveral, Florida ~ ~ New York, New York | |
Cruise Only from Interior £4,729pp Oceanview £4,969pp Balcony £7,369pp Suite £11,129pp Fly/Cruise | |
Fly/Cruise from Interior £6,239pp Oceanview £6,479pp Balcony £8,879pp Suite £12,639pp Fly/Cruise |
15th September 2025 for 16 nights | |
Grand Princess | |
Los Angeles, California ~ Manzanillo, Mexico ~ Huatulco (Santa María Huatulco) ~ Puerto Chiapas ~ Puntarenas ~ Fuerte Amador ~ ~ Aruba ~ Fort Lauderdale, Florida | |
Cruise Only from Interior £1,099pp Oceanview £1,199pp Balcony £1,639pp Suite £2,239pp Please Call for Flights |
15th September 2025 for 27 nights | |
Grand Princess | |
Los Angeles, California ~ Manzanillo, Mexico ~ Huatulco (Santa María Huatulco) ~ Puerto Chiapas ~ Puntarenas ~ Fuerte Amador ~ ~ Aruba ~ Fort Lauderdale, Florida ~ Grand Turk Island ~ Amber Cove ~ Bonaire ~ Curaçao ~ Aruba ~ Saint Kitts ~ Saint Thomas ~ San Juan (Puerto Rico) | |
Cruise Only from Interior £1,619pp Oceanview £1,799pp Balcony Call Suite Call Please Call for Flights |
18th September 2025 for 40 nights | |
Queen Elizabeth | |
Seattle, Washington ~ Ketchikan, Alaska ~ Tracy Arm, Alaska ~ Juneau, Alaska ~ Sitka, Alaska ~ Victoria, British Columbia ~ Seattle, Washington ~ San Francisco, California ~ Los Angeles, California ~ Cabo San Lucas ~ Puntarenas ~ ~ Cartagena ~ Aruba ~ Miami, Florida ~ San Juan (Puerto Rico) ~ Saint John's ~ Castries ~ Bridgetown ~ Sint Maarten ~ Tortola ~ Miami, Florida | |
Cruise Only from Interior £3,799pp Oceanview £4,549pp Balcony £5,499pp Suite £13,849pp Fly/Cruise | |
Fly/Cruise from Interior £5,209pp Oceanview £5,959pp Balcony £6,909pp Suite £15,259pp Fly/Cruise |
18th September 2025 for 28 nights | |
Queen Elizabeth | |
Seattle, Washington ~ Ketchikan, Alaska ~ Tracy Arm, Alaska ~ Juneau, Alaska ~ Sitka, Alaska ~ Victoria, British Columbia ~ Seattle, Washington ~ San Francisco, California ~ Los Angeles, California ~ Cabo San Lucas ~ Puntarenas ~ ~ Cartagena ~ Aruba ~ Miami, Florida | |
Cruise Only from Interior £2,899pp Oceanview £3,449pp Balcony £4,049pp Suite £9,849pp Fly/Cruise | |
Fly/Cruise from Interior £4,309pp Oceanview £4,859pp Balcony £5,459pp Suite £11,259pp Fly/Cruise |
Fusion Cruises when selling travel arrangements is a trading name of The Midcounties Co-operative Ltd. Fusion Cruises is an Accredited Body Member of Midcounties Co-operative Travel Consortium. (ABTA:P6652, ATOL:6053).
Book with Confidence. We are a Member of ABTA which means you have the benefit of ABTA’s assistance and Code of Conduct.
Some of the flights and flight-inclusive holidays on this website are financially protected by the ATOL scheme but ATOL protection does not apply to all holiday and travel services offered on this website. This website will provide you with information on the protection that applies in the case of each holiday and travel service offered before you make your booking. If you do not receive an ATOL Certificate then the booking will not be ATOL protected. If you do receive an ATOL Certificate but all parts of your trip are not listed on it, those parts will not be ATOL protected. Please see our booking conditions for information, or for more information about financial protection and the ATOL Certificate go to: www.caa.co.uk