From San Francisco to San Francisco

With its myriad hills and spectacular bay, San Francisco beguiles with natural beauty, vibrant neighborhoods, and contagious energy. From the hipster Mission District to the sassy Castro, from bustling Union Square to enduring Chinatown, this dynamic town thrives on variety. The city makes it wonderfully easy to tap into the good life, too: between San Francisco's hot arts scene, tempting boutiques, parks perfect for jogging or biking, and all those stellar locavore restaurants and cocktail bars, it's the ultimate destination for relaxed self-indulgence.

Unlike most cities of Southeast Alaska, Haines can be reached by road. With a population of 2,200, Haines lies in the upper northern reaches of the Inside Passage and is an important access point to the Yukon Territory and Interior Alaska. While cruising into Haines, see the Lynn Canal, the longest and deepest fjord in North America. Once in town, mountains seem to surround you on all sides while the jagged cathedral peaks of the Chilkat Mountains loom over Fort Seward. Haines has two distinct personalities. On the north side of the Haines Highway is the section of Haines that developed around the Presbyterian mission. After its missionary beginnings, it served as the trailhead for the Jack Dalton Trail into the Yukon during the 1897 gold rush to the Klondike. South of the highway, the town resembles a military post, which is exactly what it was for nearly half a century. In 1903 the U.S. Army established Fort William Henry Seward at Portage Cove just south of town. The post (renamed Chilkoot Barracks in 1922) was the only military base in the territory until World War II. In 1939, the army built the Alaska Highway and the Haines Highway to connect Alaska with the other states. Today, the community of Haines is recognized for the Native American dance and culture center at Fort Seward as well as for its superb fishing, camping and outdoor recreation.

Juneau, Alaska's capital and third-largest city, is on the North American mainland but can't be reached by road. Bounded by steep mountains and water, the city’s geographic isolation and compact size make it much more akin to an island community such as Sitka than to other Alaskan urban centers, such as Fairbanks or Anchorage. Juneau is full of contrasts. Its dramatic hillside location and historic downtown buildings provide a frontier feeling, but the city's cosmopolitan nature comes through in fine museums, noteworthy restaurants, and a literate and outdoorsy populace. The finest of the museums, the Alaska State Museum, is scheduled to reopen in May 2016 on its old site as the expanded Alaska State Library, Archives, and Museum (SLAM) following several years of planning and exhibit research. Another new facility, the Walter Soboleff Center, offers visitors a chance to learn about the indigenous cultures of Southeast Alaska–-Tlingit, Haida, and Tsimshian. Other highlights include the Mt. Roberts Tramway, plenty of densely forested wilderness areas, quiet bays for sea kayaking, and even a famous drive-up glacier, Mendenhall Glacier. For goings-on, pick up the Juneau Empire (www.juneauempire.com), which keeps tabs on state politics, business, sports, and local news.

Ketchikan is famous for its colorful totem poles, rainy skies, steep–as–San Francisco streets, and lush island setting. Some 13,500 people call the town home, and, in the summer, cruise ships crowd the shoreline, floatplanes depart noisily for Misty Fiords National Monument, and salmon-laden commercial fishing boats motor through Tongass Narrows. In the last decade Ketchikan's rowdy, blue-collar heritage of logging and fishing has been softened by the loss of many timber-industry jobs and the dramatic rise of cruise-ship tourism. With some effort, though, visitors can still glimpse the rugged frontier spirit that once permeated this hardscrabble cannery town. Art lovers should make a beeline for Ketchikan: the arts community here is very active. Travelers in search of the perfect piece of Alaska art will find an incredible range of pieces to choose from.The town is at the foot of 3,000-foot Deer Mountain, near the southeastern corner of Revillagigedo (locals shorten it to Revilla) Island. Prior to the arrival of white miners and fishermen in 1885, the Tlingit used the site at the mouth of Ketchikan Creek as a summer fish camp. Gold discoveries just before the turn of the 20th century brought more immigrants, and valuable timber and commercial fishing resources spurred new industries. By the 1930s the town bragged that it was the "salmon-canning capital of the world." You will still find some of Southeast's best salmon fishing around here. Ketchikan is the first bite of Alaska that many travelers taste. Despite its imposing backdrop, hillside homes, and many staircases, the town is relatively easy to walk through. Favorite downtown stops include the Spruce Mill Development shops and Creek Street. A bit farther away you'll find the Totem Heritage Center. Out of town (but included on most bus tours) are two longtime favorites: Totem Bight State Historical Park to the north and Saxman Totem Park to the south.

Just 40 mi (66 km) south of the Alaskan border, Prince Rupert is the largest community on British Columbia's north coast. Set on Kaien Island at the mouth of the Skeena River and surrounded by deep green fjords and coastal rain forest, Prince Rupert is rich in the culture of the Tsimshian, people who have been in the area for thousands of years. As the western terminus of Canada's second transcontinental railroad and blessed with a deep natural harbor, Prince Rupert was, at the time of its incorporation in 1910, poised to rival Vancouver as a center for trans-Pacific trade. This didn't happen, partly because the main visionary behind the scheme, Grand Trunk Pacific Railroad president Charles Hays, went down with the Titanic on his way back from a financing trip to England. Prince Rupert turned instead to fishing and forestry. A port of call for both BC and Alaska ferries, but relatively new to cruise ships, this community of 15,000 retains a laid-back, small-town air.

With its myriad hills and spectacular bay, San Francisco beguiles with natural beauty, vibrant neighborhoods, and contagious energy. From the hipster Mission District to the sassy Castro, from bustling Union Square to enduring Chinatown, this dynamic town thrives on variety. The city makes it wonderfully easy to tap into the good life, too: between San Francisco's hot arts scene, tempting boutiques, parks perfect for jogging or biking, and all those stellar locavore restaurants and cocktail bars, it's the ultimate destination for relaxed self-indulgence.